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Wan-Ping Hu Selected Research

IN6CPBD

9/2011A DC-81-indole conjugate agent suppresses melanoma A375 cell migration partially via interrupting VEGF production and stromal cell-derived factor-1α-mediated signaling.
8/2009Pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugate (IN6CPBD) has better efficacy and superior safety than the mother compound DC-81 in suppressing the growth of established melanoma in vivo.
7/2008Induction of apoptosis by DC-81-indole conjugate agent through NF-kappaB and JNK/AP-1 pathway.
6/2007DC-81-Indole conjugate agent induces mitochondria mediated apoptosis in human melanoma A375 cells.

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Wan-Ping Hu Research Topics

Disease

11Melanoma (Melanoma, Malignant)
10/2017 - 01/2003
3Neoplasms (Cancer)
01/2016 - 08/2009
2Mitochondrial Diseases (Mitochondrial Disease)
07/2014 - 06/2007
2Neoplasm Metastasis (Metastasis)
09/2011 - 08/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
02/2016
1B-Cell Leukemia (Leukemia, B Cell)
02/2016
1Leukemia
01/2016
1Basal Cell Carcinoma (Rodent Ulcer)
08/2010

Drug/Important Bio-Agent (IBA)

4IN6CPBDIBA
09/2011 - 06/2007
3DNA (Deoxyribonucleic Acid)IBA
02/2016 - 02/2006
3p38 Mitogen-Activated Protein KinasesIBA
01/2016 - 09/2011
2Phosphotransferases (Kinase)IBA
02/2016 - 09/2011
2Caspase 3 (Caspase-3)IBA
02/2016 - 06/2007
21-phenyl-3,3-dimethyltriazene (PDT)IBA
07/2014 - 08/2010
2Transcription Factor AP-1 (Transcription Factor AP 1)IBA
04/2013 - 07/2008
2indoleIBA
09/2011 - 08/2009
1TriazolesIBA
10/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
02/2016
1pyrrolo(2,1-c)(1,4)benzodiazepineIBA
02/2016
1Cytochromes c (Cytochrome c)IBA
02/2016
1AmidesIBA
02/2016
1Oxygen (Dioxygen)IBA
02/2016
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
02/2016
12-(4-aminophenyl)-7-methoxybenzothiazoleIBA
01/2016
1Type II Tumor Necrosis Factor ReceptorsIBA
01/2016
1Caspase 8 (Caspase-8)IBA
01/2016
1Adenosine Triphosphate (ATP)IBA
11/2015
1Proteins (Proteins, Gene)FDA Link
11/2015
1Autophagy-Related ProteinsIBA
11/2015
1Beclin-1IBA
11/2015
1Phospholipases A2 (Phospholipase A2)IBA
12/2014
1notexinIBA
12/2014
1AminesIBA
07/2014
1BenzothiazolesIBA
07/2014
1CarbonIBA
09/2011
1CaspasesIBA
09/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2011
1Cytostatic AgentsIBA
09/2011
1Photosensitizing Agents (Photosensitizers)IBA
08/2010
1BenzodiazepinesIBA
08/2009
1NF-kappa B (NF-kB)IBA
07/2008
1Propidium (Propidium Iodide)IBA
02/2006
1Annexin A5IBA
02/2006
1Biological ProductsIBA
01/2003
1Anti-Bacterial Agents (Antibiotics)IBA
01/2003

Therapy/Procedure

3Photochemotherapy (Photodynamic Therapy)
10/2017 - 08/2010